「肝胆膵消化器病学」は横浜市立大学附属病院の消化器内科部門です


  1. Kubota K, Sato T, Kato S, Watanabe S, Hosono K, Kobayashi N, Hisatomi K, Matsuhashi N, Nakajima A. Needle-knife precut papillotomy with a small incision over a pancreatic stent improves the success rate and reduces the complication rate in difficult biliary cannulations. J Hepatobiliary Pancreat Sci. 2013 Mar;20(3):382-8.
  2. Nonaka T, Kessoku T, Ogawa Y, Yanagisawa S, Shiba T, Sakaguchi T, Atsukawa K, Takahashi H, Sekino Y, Iida H, Endo H, Sakamoto Y, Koide T, Takahashi H, Yoneda M, Maeda S, Nakajima A, Gotoh E, Inamori M (Corresponding author). Comparative Study of 2 Different Questionnaires in Japanese Patients: The Quality of Life and Utility Evaluation Survey Technology Questionnaire (QUEST) Versus the Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease Questionnaire (FSSG). J Neurogastroenterol Motil. 2013 Jan;19(1):54-60. doi: 10.5056/jnm.2013.19.1.54. Epub 2013 Jan 8.
  3. Kadomatsu Y, Kojima T, Kohara M, Inamori M. Hepatic Portal Venous Gas Following Percutaneous Endoscopic Gastrostomy. Internal Medicine. 2013;52(1):153. Epub 2013 Jan 1.
  4. Yoneda M, Imajo K, Eguchi Y, Fujii H, Sumida Y, Hyogo H, Ono M, Suzuki Y,Kawaguchi T, Aoki N, Sata M, Kanemasa K, Kohgo Y, Saibara T, Chayama K, Itoh Y,Yoshikawa T, Anzai K, Fujimoto K, Okanoue T, Nakajima A; Japan Study Group of Nonalcoholic Fatty Liver Disease (JSG-NAFLD). Noninvasive scoring systems in patients with nonalcoholic fatty liver disease with normal alanine aminotransferase levels. J Gastroenterol. 2013 Sep;48(9):1051-60. doi: 10.1007/s00535-012-0704-y. Epub 2012 Nov 27.
  5. Tomeno W, Yoneda M, Imajo K, Suzuki K, Ogawa Y, Shinohara Y, Mawatari H,Fujita K, Shibata W, Kirikoshi H, Maeda S, Nakajima A, Saito S. Evaluation of the Liver Fibrosis Index calculated by using real-time tissue elastography for the non-invasive assessment of liver fibrosis in chronic liver diseases. Hepatol Res. 2013 Jul;43(7):735-42. doi: 10.1111/hepr.12023. Epub 2012 Dec 6.
  6. Hotta K, Kitamoto A, Kitamoto T, Mizusawa S, Teranishi H, So R, Matsuo T, Nakata Y, Hyogo H, Ochi H, Nakamura T, Kamohara S, Miyatake N, Kotani K, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Sakata T, Tanaka K, Matsuzawa Y, Nakao K, Sekine A. Replication Study of 15 Recently Published Loci for Body Fat Distribution in the Japanese Population. J Atheroscler Thromb. 2013 Apr 25;20(4):336-50. Epub 2012 Dec 7.
  7. Oshima A, Hosono K, Ito S, Sekino Y, Iida H, Nonaka T, Yamanaka S, Nakajima A, Maeda S, Gotoh E, Inamori M. Ischemic gastritis. Turk J Gastroenterol. 2014 Dec;25 Suppl 1:289-90. doi: 10.5152/tjg.2014.4114.
  8. Ida T, Morohashi T, Ohara H, Goto T, Inamori M, Nakajima A, Maeda S, Tsukumo Y, Sakamoto A, Ishikawa Y. Gastric neuroendocrine carcinoma with non-islet cell tumor hypoglycemia associated with enhanced production of insulin-like growth factor II: a case report. Internal Medicine. 2013;52(7):757-60. Epub 2013 Apr 1.
  9. Takahashi H, Yamada E, Ohkubo H, Sakai E, Higurashi T, Uchiyama T, Hosono K,Endo H, Nakajima A. Relationship of human rectal aberrant crypt foci and　formation of colorectal polyp: One-year following up after polypectomy. World J Gastrointest Endosc. 2012 Dec 16;4(12):561-4.
  10. Suzuki K, Yoneda M, Imajo K, Kirikoshi H, Nakajima A, Maeda S, Saito S. Transient elastography for monitoring the fibrosis of non-alcoholic fatty liver disease for 4 years. Hepatol Res. 2013 Sep;43(9):979-83. doi: 10.1111/hepr.12039. Epub 2013 Jan 7.
  11. Sogawa K, Noda K, Umemura H, Seimiya M, Kuga T, Tomonaga T, Nishimura M, Kanai F, Imazeki F, Takizawa H, Yoneda M, Nakajima A, Tsutsumi M, Yokosuka O, Nomura F. Serum fibrinogen alpha C-chain 5.9 kDa fragment (FIC 5.9) as a biomarker for early detection of hepatic fibrosis related to hepatitis C virus. Proteomics Clin Appl. 2013 Jun;7(5-6):424-31. doi: 10.1002/prca.201200094. Epub 2013 May 17.
  12. Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Kirikoshi H, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S. Unfolded Protein Response pathways regulate Hepatitis C Virus replication via modulation of Autophagy. Biochem Biophys Res Commun. 2013 Mar 8;432(2):326-32. doi: 10.1016/j.bbrc.2013.01.103. Epub 2013 Feb 6.
  13. Kubota K, Fujita Y, Sato T, Watanabe S, Hosono K, Yoneda M, Kirikoshi H, Hisatomi K, Matsuhashi N, Endo I, Inayama Y, Nakajima A. Tumor diameter and Ki-67 expression in biopsy could be diagnostic markers discriminating from adenoma and early stage cancer in patients with ampullary tumors. J Hepatobiliary Pancreat Sci. 2013 Jun;20(5):531-7. doi: 10.1007/s00534-013-0594-2.
  14. Takashi Uchiyama, Hirokazu Takahashi, Hiroki Endo, Eiji Sakai, Kunihiro Hosono, Yoji Nagashima, Atsushi Nakajima IL-6 Plays Crucial Roles in Sporadic Colorectal Cancer through the Cytokine Networks including CXCL7 PP. Journal of Cancer Therapy Vol.3,No 6A 874-879, Pub. November 28, 2012
  15. Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Nakamura T, Teranishi H, Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A, Hotta K.　Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan. Hum Genet. 2013 Jul;132(7):783-92. doi: 10.1007/s00439-013-1294-3. Epub 2013 Mar 28.
  16. Sakai E, Endo H, Kato S, Matsuura T, Tomeno W, Taniguchi L, Uchiyama T, Hata Y, Yamada E, Ohkubo H, Higrashi T, Hosono K, Takahashi H, Nakajima A. Capsule endoscopy with flexible spectral imaging color enhancement reduces the bile pigment effect and improves the detectability of small bowel lesions. BMC Gastroenterol. 2012;12:83.
  17. Imajo K, Yoneda M, Fujita K, Kessoku T, Tomeno W, Ogawa Y, Shinohara Y, Sekino Y, Mawatari H, Nozaki Y, Kirikoshi H, Taguri M, Toshima G, Takahashi J, Saito S, Wada K, Nakajima A. Oral choline tolerance test as a novel noninvasive method for predicting nonalcoholic steatohepatitis. J Gastroenterol. 2014 Feb;49(2):295-304. doi: 10.1007/s00535-013-0776-3. Epub 2013 Mar 16.
  18. Ohkubo H, Kessoku T, Fuyuki A, Iida H, Inamori M, Fujii T, Kawamura H, Hata Y, Manabe N, Chiba T, Kwee TC, Haruma K, Matsuhashi N, Nakajima A, Takahara T. Assessment of Small Bowel Motility in Patients With Chronic Intestinal Pseudo-Obstruction Using Cine-MRI. Am J Gastroenterol. 2013 Jul;108(7):1130-9. doi: 10.1038/ajg.2013.57. Epub 2013 Mar 19.
  19. Kubota K, Sato T, Watanabe S, Hosono K, Kobayashi N, Mori R, Taniguchi K, Matsuyama R, Endo I, Nakajima A. Covered self-expandable metal stent deployment promises safe neoadjuvant chemoradiation therapy in patients with borderline resectable pancreatic head cancer. Dig Endosc. 2014 Jan;26(1):77-86. doi: 10.1111/den.12049. Epub 2013 Mar 31.
  20. Watanabe S, Kobayashi N, Kubota K, Sato T, Kato S, Hosono K, Shimamura T, Inayama Y, Nakajima A, Endo I. A novel scoring system for arterial invasion of pancreatic body and tail cancer based on multidetector row computed tomography and biomarkers. Pancreatology. 2013 Mar-Apr;13(2):161-9. doi: 10.1016/j.pan.2012.12.364. Epub 2013 Jan 22.
  21. Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Fujita K, Kirikoshi H, Takahashi J, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S. Hepatic triglyceride lipase plays an essential role in changing the lipid metabolism in genotype 1b hepatitis C virus replicon cells and hepatitis C patients. Hepatol Res. 2013 Nov;43(11):1190-8. doi: 10.1111/hepr.12072. Epub 2013 May 10.
  22. Nonaka T, Sekino Y, Iida H, Yamada E, Ohkubo H, Sakai E, Higurashi T, Hosono K, Endo H, Koide T, Takahashi H, Fujita K, Yoneda M, Goto A, Kusakabe A, Kobayashi N, Gotoh E, Maeda S, Nakajima A, Nosaka C, Inamori M. Early Effect of Single-dose Sitagliptin Administration on Gastric Emptying: Crossover Study Using the (13)C Breath Test. J Neurogastroenterol Motil. 2013 Apr;19(2):227-32. doi: 10.5056/jnm.2013.19.2.227. Epub 2013 Apr 16.
  23. Kitamoto A, Kitamoto T, Mizusawa S, Teranishi H, So R, Matsuo T, Nakata Y, Hyogo H, Ochi H, Nakamura T, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Sakata T, Tanaka K, Matsuzawa Y, Nakao K, Sekine A, Hotta K. NUDT3 rs206936 is associated with body mass index in obese Japanese women. Endocr J. 2013 Aug 31;60(8):991-1000. Epub 2013 May 25.
  24. Kurita Y, Koide T, Watanabe S, Ogawa T, Sekino Y, Iida H, Nonaka T, Kusakabe A, Gotoh E, Maeda S, Nakajima A, Inamori M. Postpyloric decompression tube placement through a gastrostomy for malignant bowel obstruction. BMC Res Notes. 2013 Jun 3;6:217. doi: 10.1186/1756-0500-6-217. PubMed PMID: 23731859; PubMed Central PMCID: PMC3680198.
  25. Ogawa Y, Imajo K, Yoneda M, Kessoku T, Tomeno W, Shinohara Y, Kato S, Mawatari H, Nozaki Y, Fujita K, Kirikoshi H, Maeda S, Saito S, Wada K, Nakajima A. Soluble CD14 Levels Reflect Liver Inflammation in Patients with Nonalcoholic Steatohepatitis. PLoS One. 2013 Jun 7;8(6):e65211. doi:10.1371/journal.pone.0065211. Print 2013. PubMed PMID: 23762319; PubMed Central PMCID: PMC3676404.
  26. Ezuka A, Kawana K, Nagase H, Takahashi H, Nakajima A. Improvement of pneumatosis cystoides intestinalis after steroid tapering in a patient with bronchial asthma: a case report. J Med Case Rep. 2013 Jun 26;7(1):163. [Epub ahead of print] PubMed PMID: 23803391.
  27. Iida H, Ohkubo H, Inamori M, Nakajima A, Sato H. Epidemiology and clinical experience of chronic intestinal pseudo-obstruction in Japan: a nationwide epidemiologic survey. J Epidemiol. 2013;23(4):288-94. PubMed PMID: 23831693.
  28. Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kubota K, Kobayashi N, Hosono K, Watanabe S, Sekino Y, Sato T, Sasaki K, Nakaigawa N, Kubota Y, Inayama Y, Endo I, Ohno S, Maeda S, Nakajima A. aPKCλ/ι is a beneficial prognostic marker for pancreatic neoplasms. Pancreatology. 2013 Jul-Aug;13(4):360-8. doi: 10.1016/j.pan.2013.05.006. Epub 2013 May 22.
  29. Watanabe S, Sato T, Kato S, Hosono K, Kobayashi N, Nakajima A, Kubota K.　 Positioning of nasobiliary tube using magnet-loaded catheters. Endoscopy. 2013 Oct;45(10):835-7. doi: 10.1055/s-0033-1344330. Epub 2013 Jul 29.
  30. Tomeno W, Yoneda M, Imajo K, Ogawa Y, Kessoku T, Saito S, Eguchi Y, Nakajima A. Emerging drugs for non-alcoholic steatohepatitis. Expert Opin Emerg Drugs. 2013 Sep;18(3):279-90. doi: 10.1517/14728214.2013.811232. Epub 2013 Jul 13.
  31. Hirata K, Wada K, Murata Y, Nakajima A, Yamashiro T, Kamisaki Y. Critical role of leukotriene B4 receptor signaling in mouse 3T3-L1 preadipocyte differentiation. Lipids Health Dis. 2013 Aug 9;12(1):122. doi: 10.1186/1476-511X-12-122. PubMed PMID: 23937951.
  32. Taketani H, Sumida Y, Tanaka S, Imajo K, Yoneda M, Hyogo H, Ono M, Fujii H, Eguchi Y, Kanemasa K, Chayama K, Itoh Y, Yoshikawa T, Saibara T, Fujimoto K, Nakajima A; Japan Study Group of NAFLD (JSG-NAFLD). The association of insomnia with gastroesophageal reflux symptoms in biopsy-proven nonalcoholic fatty liver disease. J Gastroenterol. 2014 Jul;49(7):1163-74. doi: 10.1007/s00535-013-0871-5. Epub 2013 Aug 22.
  33. Yamada E, Ohkubo H, Higurashi T, Sakai E, Endo H, Takahashi H, Uchida E, Tanida E, Izumi N, Kanesaki A, Hata Y, Matsuura T, Fujisawa N, Komatsu K, Maeda S, Nakajima A. Visceral obesity as a risk factor for left-sided diverticulitis in Japan: a multicenter retrospective study. Gut Liver. 2013 Sep;7(5):532-8. doi: 10.5009/gnl.2013.7.5.532. Epub 2013 Jun 11.
  34. Kawamura H, Sakai E, Endo H, Taniguchi L, Hata Y, Ezuka A, Nagase H, Kessoku T, Yamada E, Ohkubo H, Higrashi T, Sekino Y, Koide T, Iida H, Nonaka T, Takahashi H, Inamori M, Maeda S, Nakajima A. Characteristics of the small bowel lesions detected by capsule endoscopy in patients with chronic kidney disease. Gastroenterol Res Pract. 2013;2013:814214. doi: 10.1155/2013/814214. Epub 2013 Aug 26.
  35. Imajo K, Yoneda M, Ogawa Y, Wada K, Nakajima A. Microbiota and nonalcoholic steatohepatitis. Semin Immunopathol. 2014 Jan;36(1):115-32. doi: 10.1007/s00281-013-0404-6. Epub 2013 Dec 14.
  36. Imajo K, Yoneda M, Kessoku T, Ogawa Y, Maeda S, Sumida Y, Hyogo H, Eguchi Y, Wada K, Nakajima A. Rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. Int J Mol Sci. 2014 Jan;36(1):115-32. doi: 10.1007/s00281-013-0404-6. Epub 2013 Dec 14.
  37. Fujisawa T, Kagawa K, Hisatomi K, Kubota K, Nakajima A, Matsuhashi N. Endoscopic papillary large-balloon dilation versus endoscopic papillary regular-balloon dilation for removal of large bile-duct stones. J Hepatobiliary Pancreat Sci. 2014 Jun;21(6):405-9. doi: 10.1002/jhbp.42. Epub 2013 Oct 14.
  38. Takahashi H, Hosono K, Endo H, Nakajima A. Colon epithelial proliferation and carcinogenesis in diet-induced obesity. J Gastroenterol Hepatol. 2013 Dec;28 Suppl 4:41-7. doi: 10.1111/jgh.12240.

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